Archives for posts with tag: unexplained infertility

I came across this in my archives. I wrote it about 2 years ago but wanted to share it again in case it could help anyone else.
I guess I should start with a disclaimer – I’m not a dr, DUH. I don’t know everything or even really that much about clotting issues but I have them so… take that. 
I have been wanting to write about this for awhile now but today I read a blog that was the final straw. As you know, I have MTHFR which is short for Methylenetetrahydrofolate Reductase – not what you thought, ha! I am homozygous with the C677T variation. All a really long way of saying that my body has a hard time methylating b vitamins especially b12, b6 and folic acid. I can’t absorb most b vitamins unless they are in their methylated forms so I have to buy a b vitamin supplement that is already broken down. (It’s called Homocystex Plus.) MTHFR also causes blood clotting issues. It’s actually more common than you think but hardly anyone gets tested for it because A) they don’t know to, B) drs are pretty ignorant about it (sorry drs. study up on this please!) C) practically nobody understands it or how to treat it, D) it’s expensive to test for and it’s usually on a whole panel that requires 14 vials of blood. ( I also just found out the other day that I had actually tested positive for Anti cardiolipin antibodies and have an elevated prothromibin time. Nobody thought it was important to tell me that but I read it in the report that I have a copy of from when I had that testing done. Thankfully, they are also treated the same as MTHFR.)
 
The fact of the matter remains, MTHFR causes infertility, implantation failure, both early and late term pregnancy loss and is incredibly easy to treat. Drs can disagree with that all they want but many other Drs agree with that statement. But you know what? It’s just one of a whole bunch of little known and “minor” issues that potentially cause clotting especially in the smallest blood vessels – in the uterus where the baby is trying to dig in and implant and where the placenta is drawing it’s life giving blood and oxygen from. 
 
MTHFR and a host of other “minor” clotting disorders can be treated by injectable blood thinners such as Heparin and Lovenox along with low dose Asprin. The blood thinners and asprin are started after ovulation/egg retrieval or asprin can be used continuously (which it usually should be if you have a clotting disorder – check with your Dr) and blood thinner shots can be started with a positive pregnancy test. You should also be on a methylated b vitamin supplement (regular b vitamins are not usable by your body) if you have MTHFR. Most drs will prescribe you a high dose vitamin b compound but it’s not as useable as just getting a high quality methylated supplement.
 
So, back to the blog that was the final straw. A woman with RPL who’s latest loss was at 20 weeks! Finally, for her SEVENTH pregnancy, somebody had the brains to check her for clotting disorders and they found that she had a “minor” one and given her “history” they decided to FINALLY treat her with Heparin. (Ya think??) Carried that baby to term. Case closed. I could also tell you the story of my friend who had at least 9 losses but carried her last baby to term and used blood thinner during that pregnancy. 
 
Obviously I’m not saying that blood thinners could prevent all loses. Definitely not!! There are genetic issues in the baby sometimes that cause losses, infections, incompetent cervix and a host of other reasons which I don’t really need to spell out, but clotting related issues can often times be treated! 
 
My RE didn’t seem to consider my issues to warrant any action. I talked to my IVF nurse though and she said if I wanted to cover all my bases, I could go on a low dose of Lovenox. I think they were mostly just letting me use it so I would feel proactive and so that they could say all my bases were covered. Turns out, as it was quite obvious during my pregnancy with Truett, blood thinner was quite important! So much so that my dose has been upped for this pregnancy. Again, I’m not saying it is fail proof. But with Tru, thank You Jesus, it helped! I hope that this time, the blood thinners will help keep my baby safe in there. Please God, protect this baby according to Your will and help it to get all the blood and oxygen flow that it needs in my womb. I pray that it will be safe in there and live and grow and be well and strong and healthy. In Jesus’ name, amen. 
 
All that to say this, if you have stumbled over this blog and you have had repeat failed IVF’s, RPL, or unexplained losses, please push your dr to test you for clotting and immune issues. And if they find ANYTHING, I don’t care how “minor” it is, (because let’s face it, when blood vessels are clogging, is there really anything “minor” about that?) and I don’t care how they feel about issues like MTHFR, get on Lovenox or Heparin and Asprin. If your dr refuses to treat you, see another dr! This is serious business. I have seen this happen SO MANY TIMES on SO MANY BLOGS. Women couldn’t get or stay pregnant, after tons of failed cycles or so many devastating losses, got treated and bam. Finally they have their baby(s). 
 
Something to think about. 
Shared: Implantation Failure, Failed IVF’s, RPL, Unexplained Infertility – Please Read This – http://wp.me/p34rdD-tI

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I guess I should start with a disclaimer – I’m not a dr, DUH. I don’t know everything or even really that much about clotting issues but I have them so… take that. 

I have been wanting to write about this for awhile now but today I read a blog that was the final straw. As you know, I have MTHFR which is short for Methylenetetrahydrofolate Reductase – not what you thought, ha! I am homozygous with the C677T variation. All a really long way of saying that my body has a hard time methylating b vitamins especially b12, b6 and folic acid. I can’t absorb most b vitamins unless they are in their methylated forms so I have to buy a b vitamin supplement that is already broken down. (It’s called Homocystex Plus.) MTHFR also causes blood clotting issues. It’s actually more common than you think but hardly anyone gets tested for it because A) they don’t know to, B) drs are pretty ignorant about it (sorry drs. study up on this please!) C) practically nobody understands it or how to treat it, D) it’s expensive to test for and it’s usually on a whole panel that requires 14 vials of blood. ( I also just found out the other day that I had actually tested slightly positive for a couple other clotting issues. Nobody thought it was important to tell me that but I read it in the report that I have a copy of from when I had that testing done. Thankfully, they are also treated the same as MTHFR.)

 

The fact of the matter remains, MTHFR causes infertility, implantation failure, both early and late term pregnancy loss and is incredibly easy to treat. Drs can disagree with that all they want but many other Drs agree with that statement. But you know what? It’s just one of a whole bunch of little known and “minor” issues that potentially cause clotting especially in the smallest blood vessels – in the uterus where the baby is trying to dig in and implant and where the placenta is drawing it’s life giving blood and oxygen from. 

 

MTHFR and a host of other “minor” clotting disorders can be treated by injectable blood thinners such as Heparin and Lovenox along with low dose Asprin. The blood thinners and asprin are started after ovulation/egg retrieval or asprin can be used continuously (which it usually should be if you have a clotting disorder – check with your Dr) and blood thinner shots can be started with a positive pregnancy test. You should also be on a methylated b vitamin supplement (regular b vitamins are not usable by your body) if you have MTHFR. Most drs will prescribe you a high dose vitamin b compound but it’s not as useable as just getting a high quality methylated supplement.

 

So, back to the blog that was the final straw. A woman with RPL who’s latest loss was at 20 weeks! Finally, for her SEVENTH pregnancy, somebody had the brains to check her for clotting disorders and they found that she had a “minor” one and given her “history” they decided to FINALLY treat her with Heparin. (Ya think??) Carried that baby to term. Case closed. I could also tell you the story of my friend who had at least 9 losses but carried her last baby to term and used blood thinner during that pregnancy. 

 

Obviously I’m not saying that blood thinners could prevent all loses. Definitely not!! There are genetic issues in the baby sometimes that cause losses, infections, incompetent cervix and a host of other reasons which I don’t really need to spell out, but clotting related issues can often times be treated! 

 

My RE didn’t seem to consider my issues to warrant any action. I talked to my IVF nurse though and she said if I wanted to cover all my bases, I could go on a low dose of Lovenox. I think they were mostly just letting me use it so I would feel proactive and so that they could say all my bases were covered. Turns out, as it was quite obvious during my pregnancy with Truett, blood thinner was quite important! So much so that my dose has been upped for this pregnancy. Again, I’m not saying it is fail proof. But with Tru, thank You Jesus, it helped! I hope that this time, the blood thinners will help keep my baby safe in there. Please God, protect this baby according to Your will and help it to get all the blood and oxygen flow that it needs in my womb. I pray that it will be safe in there and live and grow and be well and strong and healthy. In Jesus’ name, amen. 

 

All that to say this, if you have stumbled over this blog and you have had repeat failed IVF’s, RPL, or unexplained losses, please push your dr to test you for clotting and immune issues. And if they find ANYTHING, I don’t care how “minor” it is, (because let’s face it, when blood vessels are clogging, is there really anything “minor” about that?) and I don’t care how they feel about issues like MTHFR, get on Lovenox or Heparin and Asprin. If your dr refuses to treat you, see another dr! This is serious business. I have seen this happen SO MANY TIMES on SO MANY BLOGS. Women couldn’t get or stay pregnant, after tons of failed cycles or so many devastating losses, got treated and bam. Finally they have their baby(s). 

 

Something to think about. 

 

Rita New

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